CM Protégé PharmD System

Evaluate up to 384 solid form conditions with approximately 1 g of API in a single run!
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Preformulation, the selection of the form of an active pharmaceutical ingredient (API) suitable for formulation, is a critical part of the drug development process. The CM Protégé PharmD System performs high throughput solubility, polymorph, salt, and co-crystal screens to rapidly characterize the physiciochemical properties of therapeutic candidates in a high throughput manner.

  • Accurate automated dosing
    Precisely add small quantities of solid, liquid, slurry, and viscous reagents
  • Fully heated filtration
    Heat the source solution, the transfer line, and the Heated Filtration Assembly with 96 isolated wells for parallel filtering of process solvents to avoid cold spots
  • No manual manipulation of crystals
    Analyze solid forms by XRD, birefringence, or Raman on separate instruments directly from the proprietary glass Universal Substrate without any manual manipulation of fragile crystals
  • Flexible applications
    Perform process chemistry and reaction screening applications on the same system
  • Integrated informatics
    Use Freeslate LEA (Lab Execution and Analysis) software to create experiment designs and aggregate composition, process, analytical data in a central database for easy viewing and reporting
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